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Combining Bajakah Tampala and Propolis As An Improvement In The Treatment Of Breast Cancer

Three students from different faculties in Brawijaya University (UB) made a new finding by combining Bajakah Tampala & Propolis as an improvement in the treatment of breast cancer.

Three students from different faculties in Brawijaya University (UB) made a new finding by combining Bajakah Tampala & Propolis as an improvement in the treatment of breast cancer. "The (molecular) docking simulation that we carried out had a combination of compounds in Bajakah Tampala and Propolis. Previously, these two plants were known for their anticancer properties," said Ellysia Hitdatania representing the research team for the treatment of breast cancer in Malang, East Java, Saturday.
They hope that through combining Bajakah Tampala & Propolis in docking simulation can increase its anticancer value and efficacy which will result as an improvement in the treatment of breast cancer that can be beneficial in medical field.

Also Read : Make Hand Sanitizer Using Bajakah Wood

Cancer is still one of the critical problems all over the world in health sector.

Nowadays, said Ellysia, cancer is still one of the critical problems all over the world in health sector, even one of the sustainable goals of the United Nations (UN) point 3, it is emphasized that We must reduce one third of deaths from non-transmissible disease, such as diabetes and cancer. Since 2008, breast cancer cases have increased by more than 20 percent, while the death rate from breast cancer has increased by 14 percent. Breast cancer is the cancer with the highest percentage of new cases (43.3 percent) and the highest percentage of deaths (12.9 percent) in women in the world. Based on data from the 2013 Basic Health Research, the prevalence of breast cancer in Indonesia reached 0.5 per 1000 women.

Starting from these problems, three students of Chemistry Department, Faculty of Mathematics and Natural Sciences (FMIPA) and Faculty of Animal Husbandry (FAPET) UB offer an update in cancer treatment, namely by combining Bajakah Tampala & Propolis as an improvement in the treatment of breast cancer. The three students are Ellysia Hitdatania (FMIPA), and Lilin Putri Jasmine and Fadilah Nurziyadaturrohmah from Fapet. They conducted the research under the guidance of Dr. Arie Srihardyastuie S.Si, M.Kes. From this research, they managed to get funding in the 2020 Community Creativity Program (PKM) organized by the Directorate of Learning and Student Affairs of the Ministry of Cultural Education.

Also Read : Known As Cure For Cancer, Bajakah Roots Seize World Achievement

Bajakah Tampala can be used in all its parts which contain antioxidants such as flavonoids, phenolics, and saponins

The Bajakah Tampala plant (Spatholobus littoralis Hassk), said Ellysia, has been the belief of the ancestors of the Dayak tribe for generations as a healer of various diseases. "From the literature we got, Bajakah Tampala can be used in all its parts which contain antioxidants such as flavonoids, phenolics, and saponins," he said. Meanwhile, another member of the team, Lilin Putri Jasmine, according to Saputera 2018 Flavonoids, phenolics and saponins can inhibit and treat breast cancer. In addition, propolis is very well known among the public for its properties and efficacies.
Meanwhile, according to Ucar and Orhan 2019, propolis can also be used as a traditional medicine to treat breast cancer cells. After the literature study from Bajakah Tampala and Propolis was obtained, said Lilin, it would be continued in a docking simulation using three target proteins to determine the optimal binding affinity for each compound.
So, not only in the form of writing, but confirmation by docking and being able to become a drug that can help the government in the health sector, especially in cancer treatment. "By combining Bajakah Tampala & Propolis as an improvement in the treatment of breast cancer.”, it was found that Bajakah Tampala and Propolis can inhibit and invade breast cancer cells," he concluded.